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Centre intégré universitaire de santé
et de services sociaux de l'Est-de-l'Île-de-Montréal

Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal



The study, diagnosis and treatment of kidney disease are at the heart of the Nephrology Department at Hôpital Maisonneuve-Rosemont. Research in Nephrology focuses on renal failure within a scientific program consolidating the fundamental, translational and clinical continuum and addresses the following main themes:

Characterization of kidney disease

Basic and translational research aim to characterize kidney diseases and their mechanisms. Researchers are very active in studying the mechanisms of fibrosis in renal failure, immunotherapy in renal failure and transplantation, and immune responses specific to glomerular diseases.


Epidemiological research aims to study, at the population level, 1) the morbidity and mortality, as well as the associated risk factors, of patients with chronic renal failure or requiring dialysis treatments; 2) the specific journey of patients starting renal replacement therapy with an emphasis on home dialysis modalities; and 3) the evolution of glomerular diseases and their treatments via the Glomerular Disease Registry. Our researchers are involved in projects using both national and international databases.

Evaluative research and patient-centered research

This theme aims to understand how the delivery of care and services, innovations, technologies and treatments influence the experience of care and the quality of life of patients and their relatives. Diverse research approaches are required to assess the experience of care of patients and their families, in order to provide the highest quality care and services. Projects using mixed methods carried out in residential and long-term care facilities and home support in Quebec have led to significant reductions in hospitalizations and emergency transfers for these vulnerable individuals. In nephrology, mixed-design studies assess the experience and quality of life of patients and their relatives living with advanced chronic kidney disease.

Basic researchers and clinicians are very active in national and international committees, and participate in more than thirty studies, either academic or in connection with the pharmaceutical industry. They are also members of the Nephrology Research Consortium of the University of Montreal, which brings together the largest hospital institutions in the Montreal agglomeration and whose mission is to promote cutting-edge research on kidney disease.

Heads of division

Basic and clinical research - Jean-Philippe Lafrance, M.D., M.Sc.

Evaluative and patient-centered research - Kelley Kilpatrick RN, PhD