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Centre intégré universitaire de santé
et de services sociaux de l'Est-de-l'Île-de-Montréal

Centre intégré universitaire de santé et de services sociaux de l'Est-de-l'Île-de-Montréal

Simon F. Dufresne

Simon F. Dufresne

Clinical Associate Professor


Université de Montréal

Research Axes

Clinical research

Contact information

Phone: 514 252-3400, poste 4524

Dr. Dufresne is a medical specialist certified in medical microbiology and infectious diseases. He has expertise in infectious diseases in immunocompromised hosts and medical mycology.

Research Unit

Dr. Dufresne’s research focuses on the epidemiology, diagnosis and treatment of infectious diseases associated with cancer and transplantation, with an emphasis on invasive fungal infections. His research activities include both laboratory and clinical/epidemiological components. Dr. Dufresne is interested in the development and optimization of fungal infection diagnostics. He also studies the incidence and risk factors of a number of opportunistic infections, including invasive aspergillosis and invasive candidiasis. He is also involved in clinical trials evaluating new antimicrobial agents to prevent and treat opportunistic infections.

  • Maxime Parent-Michaud, Philippe J. Dufresne, Eric Fournier, Benjamin Folch, Christine Martineau, Sandrine Moreira, Nicolas Doucet, Louis de Repentigny, SF Dufresne. Prevalence and mechanisms of azole resistance in clinical isolates of cryptic Aspergillus section Fumigati species in a Montreal hospital, 2000 to 2013. Journal of Antimicrobial Chemotherapy (2020); 75(4) : 849-858.
  • SM Hosseini-Moghaddam, M Shokoohi, G Singh, SF Dufresne, A Jevnikar, R Prasad, A Shoker, D Kabbani, M Hebert, H Cardinal, I Houde, A Humar, D Kumar. A Multi-Center Case-Control Study of the Effect of Acute Rejection and Cytomegalovirus Infection on Pneumocystis Pneumonia (PCP) in Solid Organ Transplant Recipients. Clinical Infectious Diseases (2019); 68(8):1320-1326.
  • SF Dufresne, Donald C. Sheppard, Donald C. Cole, David W. Denning. Estimating the burden of serious fungal diseases in Canada. European Journal of Clinical Microbiology & Infectious Disease (2017); 36(6): 987-992.
  • Christian Lavallée, Annie-Claude Labbé, Jean-Daniel Talbot, Carolyn D. Alonso, Kieren A. Marr3, Sandra Cohen, Michel Laverdière and SF Dufresne. Risk Factors for the Development of Clostridium difficile Infection in Adult Allogeneic Hematopoietic Stem Cell Transplant Recipients: a single-center study in Québec, Canada. Transplant Infectious Diseases (2017); 19(1).
  • Dufresne P, Moonjely SS, Ozaki K, Tremblay C, Laverdière M and SF Dufresne. High frequency of pathogenic Aspergillus species among nonsporulating molds from respiratory tract samples. Medical Mycology (2017); 55(2): 233-236.
  • SF Dufresne, Beauchemin S, Lavallée C, Laverdière M. Instability of Aspergillus galactomannan in stored clinical samples. Journal of Clinical Microbiology (2014); 52(12): 4435-6.
  • SF Dufresne, Marr KA, Sydnor E, Staab JF, Karp JE, Lu K, Zhang SX, Lavallée C, Perl TM, Neofytos D. Epidemiology of Candida kefyr in Patients with Hematologic Malignancies. Journal of Clinical Microbiology (2014); 52(6): 1830-7.
  • Barkati S, SF Dufresne, Bélanger S, Vadnais B, Bergeron J, Labbé AC and Laverdière M. Incidence of invasive aspergillosis following remission-induction chemotherapy for acute leukemia: a retrospective cohort study in a single canadian tertiary center. CMAJ Open (2014); 2(2): E86-93.
  • SF Dufresne, LeBlanc R, Zhang SX, Marr KA and Neofytos D. Histoplasmosis and subcutaneous nodules in a kidney transplant recipient: erythema nodosum versus fungal panniculitis. Transplant Infectious Disease (2013); 15(2): E58-63.
  • SF Dufresne, Datta K, Li X, Staab JF, Patterson TF, Dadachova E, Feldmesser M and Marr KA. Detection of urinary excreted galactomannan for diagnosis of invasive aspergillosis. PLoS One (2012); 7(8): e42736.


  • M.D.

    Université de Montréal

  • Specialist certificate in medical microbiology and infectious diseases

    Université de Montréal

  • Fellowship in transplant infectious diseases

    Johns Hopkins University