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Isabelle Brunette

Brunette, Isabelle

Full professor


Université de Montréal

Research Axes

Vision health

Contact information

Phone: 514-252-3400, poste4959


  • Janet Laganière
  • Valérie Lavastre
  • Leila Mejdoub
  • Marilyse Piché
  • Nadia Prud'homme

An ophthalmologist specializing in the cornea, Dr. Isabelle Brunette is the director of the Corneal Transplant Research Unit. A full professor in the Department of Ophthalmology at Université de Montréal, Dr. Brunette is the Charles-Albert Poissant Research Chair in Corneal Transplantation at Université de Montréal

Recognized for her ophthalmological research in Canada and internationally and a member of the BioFemtoVision research program in Canada, Dr. Brunette advocates with public and private bodies about the importance of unifying the Canadian ophthalmological research community to meet the best interests of patients. Her research aims to optimize the functional outcomes of corneal transplantation through cutting-edge technological advances in tissue engineering and femtosecond lasers.

Research Unit

Corneal Transplantation

Dr. Brunette’s research focuses on how light passes through the cornea, and she also studies the quality of the optics of the eye following excimer laser refractive surgery based on corneal topography. 

Research interests

Excimer laser photorefractive keratectomy (refractive surgery), technological advances in cataract surgery, satisfaction studies, quality of the optics of the eye, corneal topography, Fuchs’ dystrophy.


Multicentre studies to evaluate the outcomes of different types of refractive surgery; development of a questionnaire to evaluate postoperative patient satisfaction; first objective measurements of quality of optics and measurements of optical aberrations induced by refractive surgery using a Hartmann-Shack aberrometer.


Surgery – ophthalmology – transplantation and grafts/rejection. Methodology: clinical – evaluative. Pathology: glaucoma.


  • Canadian Institutes of Health Research (CIHR)
  • Funding from the Canada Foundation for Innovation (CFI)
  • FRQS Vision Health Research Network
  • Laliberté JF, Meunier J, Chagnon M, Kieffer JC, Brunette I. Construction of a 3-D atlas of corneal shape. Investigative Ophthalmology & Visual Science 2007 Mar;48(3):1072-8.
  • Proulx S, Bourget JM, Gagnon N, Martel S, Deschambeault A, Carrier P, Giasson CJ, Auger FA, Brunette I, Germain L. Optimization of the culture conditions for porcine corneal endothelial cells. Molecular Vision 2007; Apr 3;13:524-533.
  • Hick S, Laliberté JF, Meunier J, Chagnon M, Brunette I. Effects of misalignment during corneal topography. Journal of Cataract and Refractive Surgery 2007; 33:1522-1529.
  • Vidal F, Lavertu PL, Bigaouette N, Moore F, Brunette I, Giguère D, Kieffer JC, Olivié G, Ozaki T. Modelling of the energy density deposition profiles of ultrashort laser pulses focused in optical media. Journal of Physic: Conference series 2007;59:646-650.
  • Giguère D, Olivié G, Vidal F, Toetsch S, Girard G, Ozaki T, Kieffer JC, Nada O, Brunette I. Laser ablation threshold dependence on pulse duration for fused silica and corneal tissues: experiments and modeling. Journal of the Optical Society of America A Opt Image Sci Vis. 2007 Jun;24(6):1562-8.
  • Olivié G, Giguère D, Vidal F, Ozaki T, Kieffer JC, Nada O, Brunette I. Wavelength dependence of femtosecond laser ablation threshold of corneal stroma. Optics Express 2008; Vol. 16, No. 6 ; 4121-9.


  • Fellow – Corneal transplantation and refractive surgery

    Emory University, Atlanta, GA

  • Fellow – Corneal endothelium

    Mayo Clinic Rochester , MN

  • Specialist diploma in ophthalmology

    Université de Montréal

  • BSc in biology

    Université de Montréal

  • Doctor of Medicine

    Université de Montréal


  • 2016 Canadian Academy of Health Sciences
  • 2005 Personality of the week  (La Presse / Radio Canada)
  • 2003 Senior Clinical Research Scholar  (Fonds de recherche du Québec - Santé, FRQS)
  • 2003 Charles-Albert Poissant Research Chair in Corneal Transplantation  (Université de Montréal)
  • 2000 Geographical full-time medical staff member (tenure position)  (Université de Montréal)
  • 1995 Junior 1 Clinical Research Scholar  (Fonds de recherche du Québec - Santé, FRQS)
  • 1993 New Investigator Award  (Université de Montréal)
  • 1988 Cornea fellowship  (Emory University School of Medicine, Atlanta, GA)
  • 1987 Cornea fellowship  (Mayo Clinic School of Medicine, Rochester, MN)