Malignant Hematopoiesis and Epigenetic Regulation of Gene Expression
This research unit studies the mechanisms of epigenetic regulation of gene expression during hematopoiesis:
- Identification of the molecular factors and mechanisms involved in epigenetic programming and regulation of gene expression.
- The team uses genetically modified mice, embryonic stem cells and human hematopoietic cells in their research.
- Another focus is the characterization of factors that promote leukemia development. In this area, the team is studying how certain factors influence cell proliferation regulation pathways and cell death.